Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Muscimol
Muscimol is a constituent and psychoactive ingredient of the mushroom Amanita muscaria, that acts as a potent agonist of GABAA receptors.
MilliporeSigma™ Calbiochem™ Rac Inhibitor III, EHop-016
The Rac Inhibitor III, EHop-016 controls the biological activity of Rac. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ β-Secretase Inhibitor IV
β-Secretase Inhibitor IV, CAS 797035-11-1, is a cell-permeable inhibitor that binds to BACE-1 active site and blocks its proteolytic activity (IC50 = 15 nM for human BACE-1).
MilliporeSigma™ Calbiochem™ ADP-HPD, Dihydrate, Ammonium Salt
ADP-HPD, Dihydrate is an amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM).
MilliporeSigma™ Calbiochem™ 5-Fluorouracil
Potent antitumor agent.
MilliporeSigma™ Calbiochem™ Leupeptin, Hemisulfate, Synthetic
Synthetic version of the microbial-derived inhibitor Leupeptin against trypsin-like and cysteine protease activities.
MilliporeSigma™ Calbiochem™ 2-N-Hexadecanoylamino-4-nitrophenylphosphorylcholine
Synthetic chromogenic analog of sphingomyelin.
MilliporeSigma™ Calbiochem™ PP1 Analog IV, 3-IB-PP1
A cell-permeable enlarged PP1 analog that acts as a potent, ATP-competitive and reversible inhibitor of asAkt1/2/3.
MilliporeSigma™ Calbiochem™ Castanospermine, Castanospermum australe
Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins.
MilliporeSigma™ Calbiochem™ Mifepristone
A cell-permeable synthetic steroid that acts as a potent antagonist of progesterone and glucocorticoid receptors.
MilliporeSigma™ Calbiochem™ IDH2 Inhibitor, R140Q Somatic Mutant-Specific, AGI-6780
A cell-permeable inhibitor of isocitrate dehydrogenase 2 R140Q mutant-containing dimers. Has minimal effect on wild type dimer-catalyzed alpha-KG production.
MilliporeSigma™ Calbiochem™ PIKfyve Inhibitor
The PIKfyve Inhibitor, also referenced under CAS 371942-69-7, controls the biological activity of PIKfyve. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Caspase-8 Inhibitor II
The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Nrf2 Activator III, TAT-14 Peptide
The Nrf2 Activator III, TAT-14 Peptide modulates the biological activity of Nrf2. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ TX-1123
A cell-permeable, reversible, and substrate-competitive arylidene-cyclopentenedione derived tyrphostin that acts as an inhibitor for Src, eEF2-K, and PKA, and EGFR-K/PKC at much higher concentrations.